Modulation of skin cell functions by transforming growth factor-beta1 and ACTH after ultraviolet irradiation

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Modulation of skin cell functions by transforming growth factor-beta1 and ACTH after ultraviolet irradiation.

The adaptive responses in skin to ultraviolet (UV) radiation include increased cornification of keratinocytes and increased synthesis and distribution of melanin by melanocytes. The possible involvement of paracrine factors in the generation of these responses was studied in a novel two-stage culture model. Human melanocytes or keratinocytes were first irradiated or sham-irradiated and then the...

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ژورنال

عنوان ژورنال: Journal of Endocrinology

سال: 1998

ISSN: 0022-0795,1479-6805

DOI: 10.1677/joe.0.1590153